柯盛东课题组招聘两名博士后，需RNA研究经验
2018/7/18 8:30:00 学术经纬
药明康德/报道
Positions in the Ke Lab at The Jackson Laboratory, Bar Harbor, Maine
The Ke Lab has two postdoctoral associate openings (one in computational biology, and the other in RNA biology) and one Associate Research Scientist opening at The Jackson Laboratory in Bar Harbor, Maine.
The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA genomics, the Ke lab utilizes multidisciplinary approaches, including computational biology, biochemistry, innovative biotechnologies, genetics and molecular biology. We are especially interested in the fundamental mechanism of m6A RNA genomics; and regulation of m6A RNA genomics in neurological disease and cancer, using mouse and human iPS models.
(References: 1] Ke, S. et al. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006; 2] Ke, S. et al. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.)
The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA is a world leader in mammalian genetics. JAX is passionate about its mission of discovering precise genomic solutions for disease and empowering the global biomedical community in the shared quest to improve human health. JAX is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration and exceptional core services – all within a spectacular setting adjacent to Acadia National Park.
Requirements for Position #7551 Computational Biology Postdoc:
The successful candidate will develop and apply computational methods for genomic data analyses, have novel opportunities at the intersection of algorithms, data interpretation, and experimental design in close collaboration with the experimental team in the lab. A good publication record and excellent communication skills are essential. A PhD. in a quantitative area is required: computational biology, computer science, statistics, physics and/or applied math. Programming in R, Python, Perl or C++ is desired, as well as experience in genomic dataset analysis and integration.
Requirements for Position #7224 RNA Biology Postdoc:
Qualified candidates will be self-motivated and career oriented individuals, have a genuine interest in addressing complex biological questions, and have a Ph.D. or MD. degree with background in one of the following areas, including computational biology, biochemistry, molecular biology, biotechnology, neurosciences, immunology, stem cell, or cancer biology.
Requirements for Posiiton #7542 Associate Research Scientist
PhD. in a quantitative area: computational biology, computer science, statistics, physics and applied math; Programming in R, Python, Perl or C++; experience in genomic dataset analysis and integration; three (3) years of postdoctoral training or equivalent research experience, and demonstrated meritorious scientific performance; a strong publication record (two or more peer-reviewed publications); ability to integrate and apply feedback in a professional manner, prioritize and drive to results with a high emphasis on quality, and work as part of a team.
To apply, please submit (1) a cover letter describing research interests, past research accomplishments, and career goals, (2) a current CV, and (3) the contact information of three references. Please apply online at http://www.jax.org/careers. Select link for Bar Harbor position #7551, #7224 or #7542.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
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