辉瑞招聘博士后，坐标麻省
2018/9/15 7:30:00 学术经纬
药明康德/报道
太长不看版：点击“阅读原文”/“Read More”，即可访问原始招聘页面。
ROLE SUMMARY
An exciting Postdoctoral Fellowship is available in Pfizer’s Global Biomarkers discipline in Drug Safety to support broad selectivity screening of drug candidates to better selection of compounds with desired target binding properties. The postdoctoral fellow will utilize expert skills in LC-MS/MS to develop a biomarker platform that integrates targeted mass spectrometry with enrichment using chemical probes to enhance knowledge of on- or off-target pharmacology and toxicity of therapeutic candidates. This role will provide opportunities on cutting edge chemical techniques and LC-MS/MS, and to closely collaborate with different groups in Pfizer to also gain broader drug development insights. This position requires bioanalytical expertise as well as hands-on experience in chemical biology and mass spectrometry techniques. The expectation is that this work will lead to publications in top tier journals setting the foundation for a career in academia or industry.
ROLE RESPONSIBILITIES
The successful candidate will be responsible for the development and implementation of targeted LC-MS/MS methods for the measurement of target proteins (multiplexed analytes).
To set up this methodology, testing of chemical probes with different reactivity for affinity enrichment in different biological matrices will be required.
This position requires expertise in biological sample handling (particularly cell, serum and tissues), and application of complex sample preparation methodologies including click-chemistry, enzymatic digestion and antibody enrichment applied to protein mass spectrometry.
As a strong collaborator, develop partnerships with Chemical Biologist working on click-chemistry approaches as well as other LC-MS/MS team members.
Participate in various phases of mass spectrometry laboratory operations including day-to-day use, maintenance and troubleshooting of nanoflow chromatography and mass spectrometers.
Ensure all tasks and responsibilities are carried out according to scientific and ethical standards e.g. responsible for appropriate record keeping and compliance.
Publications in peer-reviewed scientific journals and external / internal presentations are expected.
QUALIFICATIONS
Qualified applicants hold a Ph.D. in Analytical Sciences, Biochemistry, Chemistry or closely related fields with 0-2 years of postdoctoral experience.
Experience in LC-MS/MS (HRMS and/or MRM) and chemical biology techniques are essential.
Strong analytical and protein biochemistry background.
Possess excellent oral/written communication skills and ability to effectively collaborate and communicate within a team environment.
Well organized, self-motivated, ability to multitask and with attention to detail.
Willingness to learn with a strong work ethic.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
癌症突破
抗癌疫苗 | 癌症地图 | KRAS | 酒精 | CAR-T 2.0 | 单细胞CAR-T | 外泌体
智慧之光
大脑逻辑 | 母爱 | 脑细胞 | 阿兹海默病血检 | 孤独 | 可乐 | 生酮饮食 | 阿兹海默病毒假说
热门前沿
膳食纤维 | 人工智能 | 耐寒 | 维生素D | 脂肪治疗 | 细菌耐药 | 性别逆转 | 延年益寿 | 细胞分裂 | 减肥新方 | 单染色体酵母 | 吃不胖的方法 | 节食与长寿
http://weixin.100md.com
返回 学术经纬 返回首页 返回百拇医药