高血糖人群的双面人生，A和B完全不一样!结局有人笑有人哭
2024/4/1 家庭医生

    

    

    

     想知道自己是否有患糖尿病的风险？

     赶快来测一测吧~

     糖尿病风险测试

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     扫描上方二维码测一测

     糖尿病知识小问答

     滑动下方屏幕查看答案

    

     1、正确答案：C

     答案解析：2023年7月4日发布的中国首个使用二甲双胍预防糖尿病的大规模前瞻性临床研究(CDPP)表明，与单纯生活方式干预相比，二甲双胍联合生活方式干预能显著降低糖尿病发生风险达17%，其带来的获益更大、更持久。

     2、正确答案：D

     答案解析：《二甲双胍临床应用专家共识(2023年版)》中指出，若无禁忌证和优先使用其他降糖药物的强适应证，二甲双胍应作为初诊2型糖尿病(T2DM)患者控制高血糖的一线用药和药物联合中的基础用药，并贯穿糖尿病的治疗全程。

    

     参考文献：

     [1] 中华医学会内分泌学分会, 中华医学会糖尿病学分会, 中国医师协会内分泌代谢科医师分会.中国成人糖尿病前期干预的专家共识(2023版)[J]. 中华糖尿病杂志, 2023, 15(6): 484-494. DOI: 10.3760/cma.j.cn115791-20230509-00188.

     [2] Safety and effectiveness of metformin plus lifestyle intervention compared with lifestyle intervention alone in preventing progression to diabetes in a Chinese population with impaired glucose regulation: a multicentre, open-label, randomised controlled trial Lancet Diabetes Endocrinol. 2023 Jul 3;DOI:https://doi.org/10.1016/S2213-8587(23)00132-8.

     [3] Li G, Zhang P, Wang J, et al. The long?term effect of lifestyle interventions to prevent diabetes in the China DaQing Diabetes Prevention Study: a 20-year follow-up study[J]. Lancet, 2008, 371(9626): 1783-1789. DOI:10.1016/S0140-6736(08)60766-7

     [4] Diabetes Prevention Program (DPP) Research Group. The Diabetes Prevention Program (DPP): description of lifestyle intervention[J]. Diabetes Care, 2002, 25(12):2165-2171. DOI: 10.2337/diacare.25.12.2165.

     [5] Diabetes Prevention Program Research Group. Long-term effects of metformin on diabetes prevention: identification of subgroups that benefited most in the diabetes prevention program and diabetes prevention program outcomes study[J]. Diabetes Care, 2019, 42(4):601-608. DOI: 10.2337/dc18-1970

     [6] de Vegt F, Dekker JM, Jager A, et al. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: The Hoorn Study[J]. JAMA, 2001,285(16):2109-2113. DOI: 10.1001/jama.285.16.2109.

     [7] 母义明，纪立农，李春霖，等.二甲双胍临床应用专家共识(2018年版)[J]. 中国糖尿病杂志. 2019, 027(003):161.

     [8] American Diabetes Association. Standards of medical care in diabetes 2018. Diabetes Care, 2018,41:S1‐S159.

     [9] Garber AJ, Abrahamson MJ, Barzilay JI, et al. Consensus statement by the American association of clinical endocrinologists and American college of endocrinology on the comprehensive type 2 diabetes management algorithm-2018 executive summary. Endocr Prct, 2018,24:91‐120.

     [10] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 中华糖尿病杂志，2021,13(4): 315-409. DOI: 10.19538/j.nk2021080106

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