【文献解读】口腔鳞癌患者的对侧颈清扫：何时该做？

【文献解读】口腔鳞癌患者的对侧颈清扫：何时该做？
2017/9/5 创新医学网

     文章来源：欧尔意 OAE 微信号

     作者：Sofina

     原文出处

     Villanueva-Alcojol L. Contralateral neck dissection in oral squamous cell carcinoma: when it should be done? Plast Aesthet Res 2016;3:181-8.

     DOI:10.20517/2347-9264.2016.14

     摘要

     口腔鳞状细胞癌(OSCC)有很高的颈部微转移，并且有由于丰富的且跨越中线的黏膜下淋巴丛，有时会双侧转移。已经有报道指出，对侧淋巴结转移是影响预后的重要因素。然而只有少数文章报道对侧淋巴结转移的发病率以及相关影响因素。口腔鳞癌的初次手术通常都会建议行单侧择区性颈清扫；而对是否要进行对侧的择区性清扫则不明确。在本次研究中，通过系统性文献回顾来评估口腔鳞癌中隐匿性对侧淋巴转移的临床及组织病理学相关危险因素的预测价值，以期能建立对侧择区性颈清扫的理论基础。

     关键词：对侧颈清扫；鳞状细胞癌；口腔；口腔癌

     Oral cavity squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes bilaterally because of the rich lymphatics in the submucosal plexus, which freely communicate across the midline. The presence of contralateral pathologic lymph nodes has been reported previously as a critical factor influencing the survival of patients. There are a few reports in the literature with regard to the rates of contralateral neck disease and the factors that may be involved in the risk with them. An elective ipsilateral neck treatment is generally recommended for initial treatment in all OSCC. However, no consensus exists whether or not to perform an elective contralateral neck dissection or radiation. In this study, a systematic review has been performed in order to evaluate the predictive value of clinical-histopathologic factors potentially related to contralateral occult lymph node metastasis in squamous cell carcinomas of the oral cavity to form a rational basis for elective contralateral neck management.

     Keywords:Contralateral neck dissection; squamous cell carcinoma; oral cavity; oral cancer

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